Misao, working as a nurse, received news that her younger brother Yuu had been hospitalized. Eager to cheer up her adorable little brother, Misao was full of spirit, but during the preparation for surgery when Yuu's pubic hair was trimmed by Misao's senior colleague Nanako, Yuu's identity as a man awakened… The next day, upon hearing that Nanako had been consulted about sex by Yuu, Misao decided to educate Yuu about sex.
